Pharmacology of GPCRs

rent-a-lab offers assays for functional-screening of G protein-coupled receptors (GPCRs):

• [³⁵S]-GTPγS-binding
  for the measurement of G protein activation (for inhibitory and stimulatory G proteins)
  
  capacity:
  1,500 data points/day

• adenylate cyclase activity
  for the investigation of stimulated cAMP production
  
  method:
  Radiotracer method with separation of product ([³²P]cAMP) from educt ([³²P]ATP) via column chromatography
  
  capacity:
  300 data points/day